They will both fit but I'd recommend a 285/45/22 if you plan to drop the truck even a little. Ride will be stiffer with less sidewall but it kind of depends on what tire you run. I had some goodyear 275/55/20s on my truck and upgraded to pro comp all terrains in the same size and the truck rides 10x better and handles quite well compared to the goodyears. The 305/45/22 will fit with a slight drop depending on what offset wheel you are running, these trucks can clear a pretty big tire without rubbage as long as your wheels have plenty of backspacing.